- The Targum writes that the significance of the number (75,000) of dead indicates that this is the number of Amalek’s descendants.
- R’ Dovid Feinstein notes that although this seems like a large number, mathematically the 75,000 enemies would only be a little under 600 people from each of the 127 states.
- Another significance to this number is noted by the Midrash (Bireishis Rabba 39:13) where it points out that Esther was 75 years old when she became queen of Persia. In her merit, these 75,000 enemies were killed.
- Perhaps this is reiterated in the fact that the Nachal Eshkol noted that the im hakollel gematria of Hadassa (5+4+60+5(+1) = 75) is equivalent to the Ben Ish Chai’s calculation of the gematria of the Yehudim (10+5+6+4+10+40=75).